The data provides an assessment of end of century climate change relative to the first decade of the current century. The geographical domain spans the entire continental US (CONUS). The quantification of end of century relative to start of century climate change results from emissions of greenhouse gases (GHGs) and urban development, separately and in tandem. In addition, simulations employing thermal mitigation strategies, including cool and evaporative roofs, and street trees, characterize the extent to which future urban heat can be reduced.